El Primetime Emmy a la millor actriu en sèrie còmica (en anglès Primetime Emmy Award for Outstanding Lead Actress in a Comedy Series) és el Premi Emmy que s'atorga anualment a la millor actuació femenina en una sèrie còmica de televisió.
Guanyadores i nominades La guanyadora de cada any es mostra sobre fons groc:
Dècada del 1950 Any Actriu Programa Personatge 1952 Lucille Ball I Love Lucy Lucy Ricardo Eve Arden Our Miss Brooks Miss Connie Brooks Imogene Coca Your Show of Shows Diversos personatges Joan Davis I Married Joan Joan Stevens Martha Raye The Colgate Comedy Hour Diversos personatges 1955 Lucille Ball I Love Lucy Lucy Ricardo Gracie Allen The George Burns and Gracie Allen Show Gracie Allen Eve Arden Our Miss Brooks Miss Connie Brooks Jean Hagen Make Room For Daddy Margaret Williams Ann Sothern Private Secretary Susie MacNamara 1956 Nanette Fabray Caesar's Hour Edie Adams The Ernie Kovacs Show Gracie Allen The George Burns and Gracie Allen Show Gracie Allen Lucille Ball I Love Lucy Lucy Ricardo Ann Sothern Private Secretary Susie MacNamara 1959 Jane Wyatt Father Knows Best Margaret Anderson Gracie Allen The George Burns and Gracie Allen Show Gracie Allen Spring Byington December Bride Lily Ruskin Ida Lupino Mr. Adams and Eve Eve Adams Donna Reed The Donna Reed Show Donna Stone Ann Sothern The Ann Sothern Show Katy O'Connor
Dècada del 1960 Any Actriu Programa Personatge 1960 Jane Wyatt Father Knows Best Margaret Anderson Donna Reed The Donna Reed Show Donna Stone Loretta Young Letter to Loretta Loretta Young 1961 Barbara Stanwyck The Barbara Stanwyck Show Josephine Little Donna Reed The Donna Reed Show Donna Stone Loretta Young Letter to Loretta Loretta Young 1962 Shirley Booth Hazel Hazel Burke Gertrude Berg The Gertrude Berg Show Donna Reed The Donna Reed Show Donna Stone Mary Stuart Search for Tomorrow Joanne Gardner Cara Williams Pete and Gladys Gladys Porter 1963 Shirley Booth Hazel Hazel Burke Lucille Ball The Lucy Show Lucy Carmichael Shirl Conway The Nurses Liz Thorpes Irene Ryan The Beverly Hillbillies Granny Mary Tyler Moore The Dick Van Dyke Show Laura Petrie 1964 Mary Tyler Moore The Dick Van Dyke Show Laura Petrie Shirley Booth Hazel Hazel Burke Patty Duke The Patty Duke Show Patty Lane Inger Stevens The Farmer's Daughter Katy Holstrum Irene Ryan The Beverly Hillbillies Granny 1965 No hi va haver premi 1966 Mary Tyler Moore The Dick Van Dyke Show Laura Petrie Lucille Ball The Lucy Show Lucy Carmichael Elizabeth Montgomery Bewitched Samantha Stephens 1967 Lucille Ball The Lucy Show Lucy Carmichael Elizabeth Montgomery Bewitched Samantha Stephens Agnes Moorehead Bewitched Endora Marlo Thomas That Girl Ann Marie 1968 Lucille Ball The Lucy Show Lucy Carmichael Barbara Feldon Get Smart Agent 99 Elizabeth Montgomery Bewitched Samantha Stephens Paula Prentiss He and She Paula Hollister Marlo Thomas That Girl Ann Marie 1969 Hope Lange The Ghost and Mrs. Muir Carolyn Muir Diahann Carroll Julia Julia Baker Barbara Feldon Get Smart Agent 99 Elizabeth Montgomery Bewitched Samantha Stephens
Dècada del 1970 Any Actriu Programa Personatge Cadena 1969-1970 Hope Lange The Ghost & Mrs. Muir Carolyn Muir ABC Elizabeth Montgomery Bewitched Samantha StephensABC Marlo Thomas That Girl Ann Marie 1970-1971 Jean Stapleton All in the Family Edith Bunker CBS Marlo Thomas That Girl Ann Marie ABC Mary Tyler Moore The Mary Tyler Moore Show Mary Richards CBS 1971-1972 Jean Stapleton All in the Family Edith Bunker CBS Sandy Duncan Funny Face Sandy StocktonCBS Mary Tyler Moore The Mary Tyler Moore Show Mary Richards 1972-1973 Mary Tyler Moore The Mary Tyler Moore Show Mary Richards CBS Jean Stapleton All in the Family Edith BunkerCBS Bea Arthur Maude Maude Findlay 1973-1974 Mary Tyler Moore The Mary Tyler Moore Show Mary Richards CBS Bea Arthur Maude Maude FindlayCBS Jean Stapleton All in the Family Edith Bunker 1974-1975 Valerie Harper Rhoda Rhoda Morgenstern CBS Jean Stapleton All in the Family Edith BunkerCBS Mary Tyler Moore The Mary Tyler Moore Show Mary Richards 1975-1976 Mary Tyler Moore The Mary Tyler Moore Show Mary Richards CBS Lee Grant Fay Fay Stewart NBC Bea Arthur Maude Maude FindlayCBS Cloris Leachman Phyllis Phyllis Lindstrom Valerie Harper Rhoda Rhoda Morgenstern 1976-1977 Bea Arthur Maude Maude Findlay CBS Jean Stapleton All in the Family Edith BunkerCBS Valerie Harper Rhoda Rhoda Morgenstern Suzanne Pleshette The Bob Newhart Show | Emily Hartley |- | Mary Tyler Moore | The Mary Tyler Moore Show| Mary Richards |- | rowspan=7 style="text-align:center" | 1977-1978 |- style="background:#FAEB86" | Jean Stapleton | All in the Family| Edith Bunker | CBS |- | Bea Arthur | Maude| Maude Findlay | rowspan=2|CBS |- | Valerie Harper | Rhoda| Rhoda Morgenstern |- | Cathryn Damon | Soap| Mary Campbell | rowspan=2|ABC |- | Katherine Helmond | Soap| Jessica Tate |- | Suzanne Pleshette | The Bob Newhart Show Emily Hartley CBS 1978-1979 Ruth Gordon (convidada) Taxi Dee Wilcox ABC Linda Lavin Alice Alice HyattCBS Jean Stapleton All in the Family Edith Bunker Katherine Helmond Soap Jessica Tate ABC Isabel Sanford The Jeffersons Louise "Weezy" Jefferson CBS
Dècada del 1980 Any Actriu Programa Personatge Cadena 1979-1980 Cathryn Damon Soap Mary Campbell ABC Katherine Helmond Soap Jessica Tate ABC Polly Holliday Flo Flo CastleberryCBS Sheree North Archie Bunker's Place Dotty Wertz Isabel Sanford The Jeffersons Louise Jefferson 1980-1981 Isabel Sanford The Jeffersons Louise Jefferson CBS Eileen Brennan Taxi Mrs. McKenzieABC Cathryn DamonSoap Mary Campbell Katherine Helmond Jessica Tate Lynn Redgrave House Calls Ann Atkinson CBS 1981-1982 Carol Kane Taxi Simka Dahblitz ABC Nell Carter Gimme a Break! Nellie Harper NBC Bonnie Franklin One Day at a Time Ann Romano CBS Swoosie Kurtz Love, Sidney Laurie MorganNBC Charlotte Rae The Facts of Life Edna Garrett Isabel Sanford The Jeffersons Louise Jefferson CBS 1982-1983 Shelley Long Cheers Diane Chambers NBC Nell Carter Gimme a Break! Nellie Harper NBC Mariette Hartley Goodnight, Beantown Jennifer Barnes CBS Swoosie Kurtz Love, Sidney Laurie Morgan NBC Rita Moreno 9 to 5 Violet Newstead ABC Isabel Sanford The Jeffersons Louise Jefferson CBS 1983-1984 Jane Curtin Kate & Allie Allie Lowell CBS Joanna Cassidy Buffalo Bill Jo Jo WhiteNBC Shelley Long Cheers Diane Chambers Susan Saint James Kate & Allie Kate McArdle Isabel Sanford The Jeffersons Louise Jefferson CBS 1984-1985 Jane Curtin Kate & Allie Allie Lowell CBS Phylicia Ayers-Allen The Cosby Show Clair HuxtableNBC Shelley Long Cheers Diane Chambers Susan Saint James Kate & Allie Kate McArdle Isabel Sanford The Jeffersons Louise Jefferson CBS 1985-1986 Betty White The Golden Girls Rose Nylund NBC Bea Arthur The Golden Girls Dorothy ZbornakNBC Shelley Long Cheers Diane Chambers Rue McClanahan The Golden Girls Blanche Devereaux Phylicia Rashād The Cosby Show Clair Huxtable 1986-1987 Rue McClanahan The Golden Girls Blanche Devereaux NBC Bea Arthur The Golden Girls Dorothy ZbornakNBC Blair Brown The Days and Nights of Molly Dodd Molly Bickford Dodd Jane Curtin Kate & Allie Allie Lowell CBS Betty White The Golden Girls Rose Nylund NBC 1987-1988 Bea Arthur The Golden Girls Dorothy Zbornak NBC Kirstie Alley Cheers Rebecca HoweNBC Blair Brown The Days and Nights of Molly Dodd Molly Bickford Dodd Rue McClanahanThe Golden Girls Blanche Devereaux Betty White Rose Nylund 1988-1989 Candice Bergen Murphy Brown Murphy Brown CBS Bea Arthur The Golden Girls Dorothy Zbornak NBC Blair Brown The Days and Nights of Molly Dodd Molly Bickford Dodd Lifetime Rue McClanahanThe Golden Girls Blanche DevereauxNBC Betty White Rose Nylund
Dècada del 1990 Any Actriu Programa Personatge Cadena 1989-1990 Candice Bergen Murphy Brown Murphy Brown CBS Kirstie Alley Cheers Rebecca Howe NBC Blair Brown The Days and Nights of Molly Dodd Molly Bickford Dodd Lifetime Delta Burke Designing Women Suzanne Sugarbaker CBS Betty White The Golden Girls Rose NylundNBC 1990-1991 Kirstie Alley Cheers Rebecca Howe NBC Candice Bergen Murphy Brown Murphy Brown CBS Blair Brown The Days and Nights of Molly Dodd Molly Bickford Dodd Lifetime Delta Burke Designing Women Suzanne Sugarbaker CBS Betty White The Golden Girls Rose Nylund NBC 1991-1992 Candice Bergen Murphy Brown Murphy Brown CBS Kirstie Alley Cheers Rebecca Howe NBC Roseanne Arnold Roseanne Roseanne Conner ABC Tyne Daly Wings Mimsy Borogroves NBC Marion Ross Brooklyn Bridge Sophie Berger CBS Betty White The Golden Girls Rose NylundNBC 1992-1993 Roseanne Arnold Roseanne Roseanne Conner ABC Kirstie Alley Cheers Rebecca Howe NBC Candice Bergen Murphy Brown Murphy Brown CBS Helen Hunt Mad About You Jamie Buchman NBC Marion Ross Brooklyn Bridge Sophie Berger CBS 1993-1994 Candice Bergen Murphy Brown Murphy Brown CBS Roseanne Barr Roseanne Roseanne Conner ABC Helen Hunt Mad About You Jamie Buchman NBC Annie Potts Love & War Dana Palladino CBS Patricia Richardson Home Improvement Jill Taylor ABC 1994-1995 Candice Bergen Murphy Brown Murphy Brown CBS Roseanne Barr Roseanne Roseanne ConnerABC Ellen DeGeneres Ellen Ellen Morgan Helen Hunt Mad About You Jamie Buchman NBC Cybill Shepherd Cybill Cybill Sheridan CBS 1995-1996 Helen Hunt Mad About You Jamie Buchman NBC Ellen DeGeneres Ellen Ellen Morgan ABC Fran Drescher The Nanny Fran Fine CBS Patricia Richardson Home Improvement Jill Taylor ABC Cybill Shepherd Cybill Cybill Sheridan CBS 1996-1997 Helen Hunt Mad About You Jamie Buchman NBC Ellen DeGeneres Ellen Ellen Morgan ABC Fran Drescher The Nanny Fran Fine CBS Patricia Richardson Home Improvement Jill Taylor ABC Cybill Shepherd Cybill Cybill Sheridan CBS 1997-1998 Helen Hunt Mad About You Jamie Buchman NBC Kirstie Alley Veronica's Closet Veronica Chase NBC Ellen DeGeneres Ellen Ellen MorganABC Jenna Elfman Dharma & Greg Dharma Montgomery Calista Flockhart Ally McBeal Ally McBeal Fox Patricia Richardson Home Improvement Jill Taylor ABC 1998-1999 Helen Hunt Mad About You Jamie Buchman NBC Jenna Elfman Dharma & Greg Dharma Montgomery ABC Calista Flockhart Ally McBeal Ally McBeal Fox Patricia Heaton Everybody Loves Raymond Debra Barone CBS Sarah Jessica Parker Sex and the City Carrie Bradshaw HBO
Dècada del 2000